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| DATE | OPPONENT | SCORE | ATS | OU | RECAP |
| 11/12/2011 | vs St. Francis NY | W 75 - 71 | | | Recap |
| 11/17/2011 | at Virginia Commonwe | W 69 - 54 | W (3) | U (133) | Recap |
| 11/18/2011 | at Saint Joseph's | W 78 - 70 | W (-1½) | O (130½) | Recap |
| 11/20/2011 | at Northwestern | L 80 - 73 | L (4) | O (137) | Recap |
| 11/22/2011 | vs Yale | W 73 - 62 | W (-8½) | U (140) | Recap |
| 11/26/2011 | vs Saint Peter's | W 63 - 54 | L (-13½) | U (127½) | Recap |
| 12/02/2011 | vs Auburn | W 81 - 59 | W (-8½) | O (138) | Recap |
| 12/06/2011 | vs NJIT | W 78 - 48 | | | Recap |
| 12/10/2011 | vs Wake Forest | W 68 - 54 | W (-11½) | U (145) | Recap |
| 12/18/2011 | vs Mercer | W 80 - 77 | | | Recap |
| 12/21/2011 | at Dayton | W 69 - 64 | W (5½) | O (131½) | Recap |
| 12/23/2011 | at Longwood | W 87 - 61 | | | Recap |
| 12/28/2011 | at Syracuse | L 75 - 49 | L (14½) | U (138½) | Recap |
| 12/30/2011 | vs West Virginia | W 67 - 48 | W (1½) | U (136½) | Recap |
| 01/03/2012 | vs Connecticut | W 75 - 63 | W (3) | O (134½) | Recap |
| 01/07/2012 | at Providence | W 66 - 57 | W (-3) | U (133½) | Recap |
| 01/10/2012 | vs DePaul | W 94 - 73 | W (-11) | O (150) | Recap |
| 01/13/2012 | at South Florida | L 56 - 55 | L (-2) | U (122½) | Recap |
| 01/18/2012 | at Villanova | L 84 - 76 | L (1½) | O (138½) | Recap |
| 01/25/2012 | vs Notre Dame | L 55 - 42 | L (-7) | U (129½) | Recap |
| 01/28/2012 | vs Louisville | L 60 - 51 | L (-1) | U (131) | Recap |
| 01/31/2012 | at Marquette | L 66 - 59 | W (8) | U (138½) | Recap |
| 02/04/2012 | at Connecticut | L 69 - 46 | L (8½) | U (125½) | Recap |
| 02/08/2012 | at Rutgers | W 59 - 54 | W (1) | U (127) | Recap |
| 02/12/2012 | vs Pittsburgh | W 73 - 66 | W (-2) | O (127) | Recap |
| 02/14/2012 | vs St. John's | W 94 - 64 | W (-9) | O (134) | Recap |
| 02/18/2012 | at Cincinnati | L 62 - 57 | W (6) | U (130½) | Recap |
| 02/21/2012 | vs Georgetown | W 73 - 55 | W (2) | O (125) | Recap |
| 02/25/2012 | vs Rutgers | L 77 - 72 | L (-7½) | O (130) | Recap |
| 03/03/2012 | at DePaul | L 86 - 58 | L (-5½) | U (149½) | Recap |
| 03/06/2012 | vs Providence | W 79 - 47 | W (-6) | U (137½) | Recap |
| 03/07/2012 | at Louisville | L 61 - 55 | L (4) | U (126) | Recap |
| 03/13/2012 | vs Stony Brook | W 63 - 61 | L (-9) | U (126½) | Recap |
| 03/17/2012 | vs Massachusetts | L 77 - 67 | L (-7½) | U (151) | Recap |
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